211 articles — showing all

Leaving the Ventilator Connected: A Randomized Trial of Continued Non-Invasive Ventilation During Elective Neonatal Intubation
Randomized Clinical TrialPhysiology

Leaving the Ventilator Connected: A Randomized Trial of Continued Non-Invasive Ventilation During Elective Neonatal Intubation

When a premature baby in intensive care needs a breathing tube placed, doctors have traditionally removed the baby's nasal breathing support first — leaving the baby with no help at all for the twenty to forty seconds the procedure takes. A 2025 randomized trial in eastern India tested the obvious…

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Extending the Warm Chain Beyond Admission: A Single-Cycle Quality-Improvement Bundle Against Neonatal Hypothermia in Rural Ethiopia
Health Systems & PolicyEpidemiology & Biostatistics

Extending the Warm Chain Beyond Admission: A Single-Cycle Quality-Improvement Bundle Against Neonatal Hypothermia in Rural Ethiopia

A hospital in rural Ethiopia showed that a bundle of simple, inexpensive warming steps — training staff, warming rooms before birth, dressing babies in hats and socks, and checking temperatures carefully — helped newborns arrive and stay warmer during their hospital stay. Babies were warmer on…

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When a Low Number Is Not a Low-Flow State: Grading the Evidence on Treating Isolated Hypotension in Very Preterm Infants
Meta-analysisEpidemiology & Biostatistics

When a Low Number Is Not a Low-Flow State: Grading the Evidence on Treating Isolated Hypotension in Very Preterm Infants

When a premature baby in intensive care shows a low blood pressure but is otherwise pink, warm, and doing well, doctors have long debated whether to treat that number at all. A 2025 international review pulled together 44 studies to answer the question and reached a careful, reassuring conclusion…

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Ranking Drug-Free Comfort Measures for the Newborn Heel Stick
Epidemiology & BiostatisticsNeuroscience

Ranking Drug-Free Comfort Measures for the Newborn Heel Stick

Newborn babies need small blood tests in their first days, and the most common one is the "heel prick" — a quick lance to the heel to collect a few drops of blood. It is brief, but it does hurt. A 2025 research review gathered the best trials on drug-free ways to comfort babies during this…

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Two Nomograms for Neonatal Sepsis: What a Single-Centre Chinese Cohort Can and Cannot Tell Us About Multivariable Diagnosis
Epidemiology & BiostatisticsMicrobiology

Two Nomograms for Neonatal Sepsis: What a Single-Centre Chinese Cohort Can and Cannot Tell Us About Multivariable Diagnosis

Doctors caring for newborns face a problem that has never had a clean solution: the early signs of a serious blood infection look almost exactly like the ordinary, harmless unsettledness of a baby in the first days of life. A team at a children's hospital in China has now built two scoring charts…

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Universal Nirsevimab and the Residual Burden of Prematurity and Household Exposure
PharmacologyEpidemiology & Biostatistics

Universal Nirsevimab and the Residual Burden of Prematurity and Household Exposure

A new antibody shot called nirsevimab, given to newborns before they leave the hospital, dramatically lowered the number of babies hospitalized with the winter virus RSV in a large real-world study from Italy. Across nearly 14,000 babies, hospital admissions for RSV lung infections dropped by about…

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A Biomarker That Is Not a Target: Endogenous Erythropoietin, Transfusions, and Injury to the Extremely Preterm Eye and Brain
NeuroscienceEpidemiology & Biostatistics

A Biomarker That Is Not a Target: Endogenous Erythropoietin, Transfusions, and Injury to the Extremely Preterm Eye and Brain

A large new analysis of nearly a thousand extremely premature babies found that the blood transfusions these infants often need were linked to a higher chance of serious eye disease and brain injury, while the babies' own natural levels of a hormone called erythropoietin mostly reflected how much…

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Recorded Parental Song and Respiratory Stability in Very Preterm Infants
Randomized Clinical TrialNeuroscience

Recorded Parental Song and Respiratory Stability in Very Preterm Infants

A small study from Japan found that playing a recording of a parent singing helped premature babies breathe a little more calmly. Babies who listened to their own parent's recorded song for 30 minutes a day showed a modest, measurable drop in how fast they were breathing, and a very slight rise in…

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Estimating Serum Phosphate in Very Preterm Infants From Routine Blood Gas Data
Nutrition & MetabolismEpidemiology & Biostatistics

Estimating Serum Phosphate in Very Preterm Infants From Routine Blood Gas Data

Very premature babies often develop a low level of phosphate — a mineral essential for growth — in their first week of life, and a Norwegian study found that one in three did. Babies who were unusually small at birth for their stage of pregnancy were affected much earlier and much more often…

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