50 articles in Immunology & Infectious Diseases

Lineages, Prematurity and Prevention: Infant Group B Streptococcal Disease Through the Lens of Two National Genomic Surveillance Programmes
Epidemiology & BiostatisticsGenetics & Genomics

Lineages, Prematurity and Prevention: Infant Group B Streptococcal Disease Through the Lens of Two National Genomic Surveillance Programmes

Group B Strep is a common bacterium that can cause rare but serious infections in young babies. Two large studies from the Netherlands and Denmark found that these infections have become more common in Dutch babies despite antibiotics given during labour, that babies born very early tend to fall…

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Can Tolerance Be Taught Before Weaning? A Randomised Test of High Maternal Egg and Peanut Intake During Pregnancy and Lactation
Randomized Clinical TrialImmunology

Can Tolerance Be Taught Before Weaning? A Randomised Test of High Maternal Egg and Peanut Intake During Pregnancy and Lactation

Many parents-to-be with allergies in the family wonder whether eating more egg and peanut while pregnant and breastfeeding could protect their baby. A large Australian study of 2,137 pregnant women found that babies whose mothers ate lots of these foods were about as likely to have egg or peanut…

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Same Pathogen, Different Prescription: International Variation in Antimicrobial Duration and Sepsis Management for Infants Born Before 29 Weeks
Health Systems & PolicyEpidemiology & Biostatistics

Same Pathogen, Different Prescription: International Variation in Antimicrobial Duration and Sepsis Management for Infants Born Before 29 Weeks

When a very premature baby develops a blood infection, doctors around the world agree that antibiotics are needed, but they do not agree on how long to give them. A survey of 382 neonatal intensive care units in 12 neonatal networks found that the usual course ranged from under a week to three…

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Procalcitonin-Guided Antibiotic Discontinuation in Neonatal Late-Onset Sepsis: Shorter Courses, Underpowered Safety Estimates
Randomized Clinical TrialMicrobiology

Procalcitonin-Guided Antibiotic Discontinuation in Neonatal Late-Onset Sepsis: Shorter Courses, Underpowered Safety Estimates

When a baby in neonatal intensive care develops an infection, antibiotics can be life-saving, but giving them for longer than needed can also cause harm. A large French study of 504 babies found that checking a blood marker called procalcitonin every two days helped doctors stop antibiotics about…

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Weak Cry, Poor Feeding and Slow Capillary Refill: Pooled Evidence on Which Clinical Signs Mark Death and Sepsis in Infants Under Two Months
Meta-analysisEpidemiology & Biostatistics

Weak Cry, Poor Feeding and Slow Capillary Refill: Pooled Evidence on Which Clinical Signs Mark Death and Sepsis in Infants Under Two Months

Babies in their first two months can become seriously ill from infection very quickly, and in many parts of the world health workers must decide who needs hospital care by looking at the baby rather than by running laboratory tests. A large 2026 review of 52 studies and more than 140,000 babies…

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Beyond the Positive Blood Culture: Hidden Infection, Heterogeneous Organ Dysfunction and Long-Term Neurological Risk in Neonatal Sepsis
MicrobiologyEpidemiology & Biostatistics

Beyond the Positive Blood Culture: Hidden Infection, Heterogeneous Organ Dysfunction and Long-Term Neurological Risk in Neonatal Sepsis

Doctors usually decide whether a newborn has a serious infection by growing germs from a blood sample, but this test can miss infections and says little about how sick a baby is. Three new studies from Germany, the United States and Denmark suggest that testing the umbilical cord can reveal hidden…

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Maternal RSVpreF Vaccination, Infant Nirsevimab, or Both: Safety, Effectiveness and Population Impact from Randomised Trial to National Programmes
Randomized Clinical TrialEpidemiology & Biostatistics

Maternal RSVpreF Vaccination, Infant Nirsevimab, or Both: Safety, Effectiveness and Population Impact from Randomised Trial to National Programmes

Babies can now be protected from RSV, a common virus that can make very young babies seriously ill, in two ways: a vaccine given to the mother during pregnancy, or a protective antibody injection given to the baby. Three studies from 2026, from the United States, Australia and Europe, show that…

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