11 articles in Cardiovascular

The Heart Around the Operation: Three 2026 Echocardiographic Cohorts Redraw the Perioperative Haemodynamic Map in Congenital Diaphragmatic Hernia
PathophysiologyPhysiology

The Heart Around the Operation: Three 2026 Echocardiographic Cohorts Redraw the Perioperative Haemodynamic Map in Congenital Diaphragmatic Hernia

When a baby is born with a hole in the diaphragm, the heart is squeezed as well as the lungs. Three studies published in 2026 used bedside ultrasound to follow how the heart works before and after the operation that closes the gap. Together they show that the right side of the heart recovers…

scientificclinicalfamily
A blood pressure problem that begins in the incubator and is still there at eighteen
Epidemiology & BiostatisticsPharmacology

A blood pressure problem that begins in the incubator and is still there at eighteen

Babies born too early sometimes develop high blood pressure in newborn intensive care, and doctors treat it — but no guideline says which medicine to use. Two 2025 studies fill in opposite ends of the picture: one found a large American hospital reached for the same drug about 61% of the time, out…

scientificclinicalfamily
Reading the Newborn Heart in the First 72 Hours: Early Haemodynamic Phenotype and the Risk of Death or Severe Bronchopulmonary Dysplasia
PhysiologyEpidemiology & Biostatistics

Reading the Newborn Heart in the First 72 Hours: Early Haemodynamic Phenotype and the Risk of Death or Severe Bronchopulmonary Dysplasia

When a baby is born more than eleven weeks early, the first few days are a time of intense watching. Doctors in Riyadh recently studied whether a quick, painless ultrasound scan of the heart, done in the first three days of life, could reveal which of these fragile babies were facing the hardest…

scientificclinicalfamily
When a Low Number Is Not a Low-Flow State: Grading the Evidence on Treating Isolated Hypotension in Very Preterm Infants
Meta-analysisEpidemiology & Biostatistics

When a Low Number Is Not a Low-Flow State: Grading the Evidence on Treating Isolated Hypotension in Very Preterm Infants

When a premature baby in intensive care shows a low blood pressure but is otherwise pink, warm, and doing well, doctors have long debated whether to treat that number at all. A 2025 international review pulled together 44 studies to answer the question and reached a careful, reassuring conclusion…

scientificclinicalfamily
Speed of Pulmonary Pressure Reduction Separates Two Oral Vasodilators in PPHN
PharmacologyRandomized Clinical Trial

Speed of Pulmonary Pressure Reduction Separates Two Oral Vasodilators in PPHN

Some newborns cannot get enough oxygen because the blood vessels in their lungs stay tightly closed after birth — a condition called persistent pulmonary hypertension of the newborn. The best treatment, a gas called inhaled nitric oxide, is unavailable in most hospitals worldwide. A trial in Pune…

scientificclinicalfamily
Early Ibuprofen Does Not Improve Short- or Long-Term Outcomes in Extremely Preterm Infants With a Large Patent Ductus Arteriosus
Randomized Clinical TrialPharmacology

Early Ibuprofen Does Not Improve Short- or Long-Term Outcomes in Extremely Preterm Infants With a Large Patent Ductus Arteriosus

A large UK study called Baby-OSCAR followed 653 very premature babies who had a common heart-related condition, and it found that giving the medicine ibuprofen early — to close an open blood vessel near the heart — did not help babies survive better, breathe better, or develop better than giving a…

scientificclinicalfamily
Patent Ductus Arteriosus: History, Treatment Evolution, and the Road to TREOCAPA
Randomized Clinical Trial

Patent Ductus Arteriosus: History, Treatment Evolution, and the Road to TREOCAPA

Before a baby is born, it doesn't use its lungs — it gets all the oxygen it needs from its mother through the placenta. Because the lungs aren't working yet, the fetal body has a clever shortcut: a small blood vessel called the ductus arteriosus that diverts blood away from the lungs and straight…

scientificclinicalfamily