211 articles — showing all

Citicoline as an Adjunct Neuroprotectant in Neonates with Moderate-to-Severe Hypoxic-Ischaemic Encephalopathy Ineligible for Cooling
Randomized Clinical TrialPharmacology

Citicoline as an Adjunct Neuroprotectant in Neonates with Moderate-to-Severe Hypoxic-Ischaemic Encephalopathy Ineligible for Cooling

When a baby's brain is briefly starved of oxygen and blood flow around the time of birth, the result can be a serious condition called hypoxic-ischaemic encephalopathy, or HIE. The one proven treatment — cooling the baby's body for three days — only works for certain infants and must start within…

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When Developmental Care Stops Being a Programme and Becomes the Ward Routine
Randomized Clinical TrialNeuroscience

When Developmental Care Stops Being a Programme and Becomes the Ward Routine

When a hospital in Ukraine changed how its neonatal unit worked — letting parents in around the clock, putting babies skin-to-skin on their parents' chests, protecting sleep, dimming lights and lowering noise — the premature babies cared for afterwards had less infection, less bleeding in the…

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A Breath Test to Right-Size Phototherapy: A Randomized Trial of ETCOc-Adjusted Risk Categorization in Neonatal Hyperbilirubinemia
Randomized Clinical TrialPathophysiology

A Breath Test to Right-Size Phototherapy: A Randomized Trial of ETCOc-Adjusted Risk Categorization in Neonatal Hyperbilirubinemia

A quick, painless breath test can help doctors safely give fewer newborns light treatment for jaundice. In a study of 2,500 babies, adding this test to the usual jaundice assessment lowered the share who needed the lights from about 22 out of 100 to about 19 out of 100 — without any increase in…

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A Landmark on the Face, Measured Against the Film: Oro-Helix Length Outperforms Naso-Tragus Length and Gestational-Age Tables for Endotracheal Tube Depth in Infants ≤1,500 g
Anatomy & EmbryologyEpidemiology & Biostatistics

A Landmark on the Face, Measured Against the Film: Oro-Helix Length Outperforms Naso-Tragus Length and Gestational-Age Tables for Endotracheal Tube Depth in Infants ≤1,500 g

When a very premature baby needs a breathing tube, doctors must decide in seconds how far to push it in — and the safe zone is less than half an inch wide. A new study of 50 babies weighing under 1,500 grams found that the two methods most widely taught today tend to push the tube in slightly too…

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A Measurable Microbial Signal Without a Measurable Clinical Consequence: Early Empiric Antibiotics, the Very Preterm Gut, and Late-Onset Sepsis
MicrobiologyMeta-analysis

A Measurable Microbial Signal Without a Measurable Clinical Consequence: Early Empiric Antibiotics, the Very Preterm Gut, and Late-Onset Sepsis

Most babies born very early receive antibiotics in their first hours, because a serious infection at birth is hard to rule out and dangerous to miss. Two new studies looked at what those antibiotics do. One found small, real changes in the mix of bacteria in the baby's gut. The other, much larger…

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A Low-Technology Intervention Re-examined: Pooled Evidence That Topical Emollient Oil Promotes Weight Gain in Preterm Neonates
Epidemiology & BiostatisticsNutrition & Metabolism

A Low-Technology Intervention Re-examined: Pooled Evidence That Topical Emollient Oil Promotes Weight Gain in Preterm Neonates

Rubbing a gentle, everyday oil — such as sunflower or coconut oil — onto a premature baby's skin, often as part of a soft massage, appears to help the baby put on a little extra weight, according to a large 2024 review that pooled the results of many earlier studies. The added weight was modest, on…

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