211 articles — showing all

From Pooled Accuracy to a Working Pathway: How Newborn Bilirubin Screening for Biliary Atresia Moved From Evidence to Algorithm
Epidemiology & BiostatisticsMeta-analysis

From Pooled Accuracy to a Working Pathway: How Newborn Bilirubin Screening for Biliary Atresia Moved From Evidence to Algorithm

Biliary atresia is a rare liver condition in newborns in which the tubes that carry bile out of the liver become blocked. Surgery works best when it happens in the first six weeks of life, but most babies are still diagnosed later than that. Two recent studies suggest that a simple blood test…

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Immunising the Mother to Protect the Newborn: What Two 2025 Reviews Reveal About the Efficacy Ceiling and the Safety Blind Spot of RSVpreF Vaccination in Pregnancy
ImmunologyEpidemiology & Biostatistics

Immunising the Mother to Protect the Newborn: What Two 2025 Reviews Reveal About the Efficacy Ceiling and the Safety Blind Spot of RSVpreF Vaccination in Pregnancy

A vaccine given to a mother late in pregnancy can protect her baby from the most common cause of serious chest infections in infancy. Two medical reviews published in 2025 found that this protection is strong in the first three months of life and fades gradually afterwards, and that side effects…

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One in Ten Thousand Newborns, and the Number Is Climbing
Epidemiology & BiostatisticsMeta-analysis

One in Ten Thousand Newborns, and the Number Is Climbing

Neonatal herpes is an uncommon but serious infection that a baby can catch around the time of birth. The first worldwide study of how often it happens estimates that it affects roughly one baby in every 10,000 born, and that this number has been creeping upward by about 3.5% each year. This article…

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Neonatal Thromboembolic Disease: Rising Recognition Against a Thin Evidence Base
PathophysiologyPharmacology

Neonatal Thromboembolic Disease: Rising Recognition Against a Thin Evidence Base

Blood clots are one of the lesser-known risks of newborn intensive care. They form most often around the thin plastic tubes, called central lines, that carry nutrition and medicine into a sick baby's bloodstream. Three recent medical reports examined how often these clots happen, how doctors find…

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Hydrocortisone, Combined Inotropes, and the Fragile Ileum: Re-Estimating the Pharmacologic Risk Profile for Spontaneous Intestinal Perforation
PharmacologyEpidemiology & Biostatistics

Hydrocortisone, Combined Inotropes, and the Fragile Ileum: Re-Estimating the Pharmacologic Risk Profile for Spontaneous Intestinal Perforation

Spontaneous intestinal perforation is a small hole that can open in the bowel of the tiniest premature babies, usually in the first week or two of life. A ten-year study of 858 extremely small newborns in Taiwan found that two common intensive-care treatments — a steroid called hydrocortisone, and…

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