Category

Hematology & Oncology

2 articles

Harm That Outlasts the NICU: Two-Year Outcomes of Liberal Versus Restrictive Platelet Transfusion in Preterm Infants
Randomized Clinical Trial

Harm That Outlasts the NICU: Two-Year Outcomes of Liberal Versus Restrictive Platelet Transfusion in Preterm Infants

A large international study followed premature babies who had low platelet counts and found that giving platelet transfusions more freely did not help them and actually caused harm that lasted into early childhood. Babies given transfusions at a more generous threshold were more likely to have died or to have a developmental problem by age two than babies given them only when their counts fell much lower. The clear lesson: for these infants, a more cautious, "wait-and-watch" approach is safer.