Category

Gastroenterology & Bilirubin

19 articles

Hydrocortisone, Combined Inotropes, and the Fragile Ileum: Re-Estimating the Pharmacologic Risk Profile for Spontaneous Intestinal Perforation
PharmacologyEpidemiology & Biostatistics

Hydrocortisone, Combined Inotropes, and the Fragile Ileum: Re-Estimating the Pharmacologic Risk Profile for Spontaneous Intestinal Perforation

Spontaneous intestinal perforation is a small hole that can open in the bowel of the tiniest premature babies, usually in the first week or two of life. A ten-year study of 858 extremely small newborns in Taiwan found that two common intensive-care treatments — a steroid called hydrocortisone, and…

A Test That Confirms Rather Than Predicts: Pooled Diagnostic Accuracy of the Direct Antiglobulin Test for Treatment-Requiring Neonatal Hyperbilirubinaemia
Meta-analysisEpidemiology & Biostatistics

A Test That Confirms Rather Than Predicts: Pooled Diagnostic Accuracy of the Direct Antiglobulin Test for Treatment-Requiring Neonatal Hyperbilirubinaemia

A common newborn blood test called the Coombs test looks for one specific cause of jaundice: antibodies from the mother attacking the baby's red blood cells. A large 2025 review pooling 28 studies and 20,935 newborns found that when the test is positive it does raise the odds a baby will need…